During most of his life, Alyssa Fraser comforts when cooking. Fraser, a former food reporter from Minnesota, used to enjoy the process of preparing his favorite chicken and vegetable recipe or pasta lots. But after replacing the popular weight loss of weight, its culinary interests seemed to disappear because it disinterpretted in food and certain types of food from Bocame in a privileged way. Many tasty foods lost their appeal, and some proteins supplied to taste too much like the “corral” from which the animal came, he says. Only a favorite wine, which generally knew crunchy and citrus, seemed strangely “vegetable.”
Similar to Fraser, other WOGOVY users (known in its generic form as a semaglutida), together with those of Ozempic (a form of semaglutida used to treat type 2 diabetes), Zepbound (generically known as the tirzepatida) and other medications that are widely called the glycagon 1 (LPG-1) that have described the peculiar peculiar peculiar glucagon peptides. GLP-1 medications initially designed to help type 2 diabetes activating insulin release-they can cause weight loss by making people feel full faster. But some people report that, in addition to an increase in satiety, they experience changes in their preferences for specific foods: they find that repulsive repulsive meats, too heavy fried foods and tasty snacks that are not stuck. In online forums and scientific surveys, some people have expressed a general loss of interest in food in general, some have only drugs have redefined food as a need instead of a joy for them. These accounts can be captured in grocery store data that suggests that people in GLP-1 medicines spend less on food, especially articles rich in calories and processed.
Some preliminary tests suggest that changes in food preferences could play a role in weight loss, but it is not clear how much such a result contributes compared to the effect of medications on satiety. And research on the phenomenon has mainly involved animal models or small humans. Experts, however, are beginning to obtain some clues about how common thesis changes change in the preference and taste of food are really among users and what could be behind them.
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A recently published study in Food quality and preference He discovered that people with GLP-1 medications reported that they reached processed foods, as well as refined grains and beef, less frequently. They also said they drank less soft drinks and other sweat drinks and increasing their fruit intake, green leafy vegetables and water. In addition, they reported having consumed about 700 calories from Fer per day. These findings are based on self -informed data, however, that sometimes they can be unreliable, says Brandon McFadden, professor in food policy economy at the University of Arkansas and co -author of the study.
In addition, Althegh GLP-1 users reported that they ate dense foods in calories, most people did not necessarily lose all desire for them. This is because beating A meal is different from Remando John Blundell, Professor Emeritus at Psychobiology at the University of Leeds in England, who did not participate in the recent document. It is possible that a person does not find a tasty food (in other words, they may not enjoy the specific sensory experience of consuming it), but still has a strong impulse of behavior to eat it. GLP-1 medications seem to involve otherwise: people still like certain foods, but they have less immediate urgency to eat.
These drarugs mimic a hormone strased glp-1, which gut naturally secrets in responsibility to food and which binds to the hormone’s recets aroud the body-inluding in brain areas involved in apopetite regulation and in reward pathways that reduce the reduce’s That reduce’S that record reduces, that reduces, that reduces, that reduces, that reduces That reduces, that reduces, that reduces, that reduces, that reduces, that reduces, that reduces, that reduces, that reduces, Researchers have Found that This is The Primary Way The Drugs make people lose weight, and some think that they could be set into the preferences of altered food.
Specific food wishes can change their deposit whether a person is general or full. For example, when you are hungry, you are more likely to want fleshy foods, high protein or, sometimes, high in fat instead of sweets, Blundell explains. “When you fill yourself, the opposite happens,” he says: A large piece of meat or a high -fat food becomes aversive, but you may feel that you have a second stomach for dessert. A plausible explanation for this, says Blundell, could be that the satisfied effect of LPG-1 drugs simply makes end of dining preferences activate. It is also possible that some aspects of drug compounds can act directly on specific food preferences through other biological mechanisms. “But the leg has been demonstrated,” says Blundell, who is working with a food company to develop foods that are tastier for people with LPG-1 measurements.
Blundell directed a small study, published in 2017, which found that the people who took Semaglutida not only reduced their general intake of daily foods, but also preferred and consumed less salty and fatty foods. Previous investigations published in 2007 showed that being full also decreases similar cravings.
But satiety alone may not explain the change in food preferences. Emerging evidence and anecdotal users accounts suggest that changes in body flavor mechanisms could also play a role. Somet Users Describes Flavors Becoming Stronger or Unpleasing While on The Mediums, Individual Though Experiences to Vary: Siobhan, Los Angeles – Based Writer, Who has bone Bean Wegovy Spray 2021 and With Hero’s Fatty Aspatty, Say’s Say’s As Privacy, Say’s Say, Say’s Say Say, Say’s Say, Say’s Say, Say’s Say, Say’s Aspatty As Privacy, Say’s Say, Says As Privacy, Say’s Say, Says As I Say says Asaofs Asay, he says. Aphricante, but his favorite food, Panang Curry, has become too bitter. “I’ve been eating that curry for 20 years,” says Siobhan. “I just didn’t know well.” The two -year user, Sarah Streby, says she can no longer stomach stomach of eggs or broccoli, and her love for spicy food has decreased to change it to change the way she cooks for the family. “Now everyone complains that food is too soft because [I] I can’t handle the spice, “she says.
At the time of publication, Novo Nordisk, the Wegovy and Ozempic manufacturer, had not responded to a request for comments from Scientific American. A spokesman for Eli Lilly, who makes the weight loss drug be Zepbound, said American scientist In an email, “we have no data to share regarding changes in the taste of food or preference between people who take medications GLP-1”. The spokesman added that the known side effects are listed on medication labels and that any person who experiences these side effects must communicate with their medical care provider.
Scientists have found GLP-1 receptors in human gustatory papillae, which hints at a possible explanation of flavor alterations, but the findings remain mixed. Some previous investigations have found that people with higher body weight tend to perceive less intense intense flavors, and some evidence suggests that this can lead people to eat more in an attempt to obtain a larger sensory reward. In the case of sweet foods, people with higher body weight can also be less able to perceive a high sugar content, thought findings in this have been contradictory. A small study presented at the 2024 annual conference of the endocrine society found that the women who took semaglutida were more sensitive to taste with those of a placebo. The brain scan showed a greater activity in a region involved in the processing of sensory rewards when participants tested something sweet, suggestion that the semagglutide can the taste of heights and make certain foods less attractive.
But another study published in March in Physiology and behavior It seems to suggest otherwise. He found that 46 people who take these medications experienced a reduced sensitivity to the five basic tastes: sweet, sour, salty, bitter and broth (or Umami), compared to people in a control group. It conforms to the studies in mice linked the activation of the reception of LPG-1 to the alterations in the perception of sweet taste, but the researchers were surprised to see that the effect on humans was broader than expected, says Richard Doty, director of the center of smell and taste or pensilvania. Previous investigations that linked GLP-1 medications with alterations in taste have mainly analyzed diabetic populations, says Doty, adds that “the approach has always been in sugar, so people do not have in the other details of sensory systems.” The suspects of the LPG-1 receptors found in the taste papillae are behind the March findings, “but we really do not know; there must be more research on that.”
For some, the effects of drugs on satiety and taste are welcome changes that facilitate food. But for others, it is more complicated. “Not only I’m not cooking or really walking an interest in food, I want it, they are sweet,” says Fraser. “And just then, if it is super sweet, I will take a bite or two, and I say, I have to leave it.” She says that salty foods have lost their attractiveness completely.
Fraser is still consulting the compensation for the improvements he has seen in his health while navigating this change and treats the loss of a beloved hobby. But “the mental burden of weight loss has been reduced considerably,” he says, “and that is worth me.”
